- The Maroon breaks the news that UChicago will have an entirely remote spring quarter on March 11.
- University of Chicago Laboratory Schools pivot to a remote spring quarter.
- Dining halls serve the last sit-down meal service on March 16.
- A Chicago Booth student is the first case of COVID-19 reported at UChicago on March 17.
- University libraries close.
- Illinois Governor J. B. Pritzker issues a stay-at-home order on March 20.
- Residence halls close on March 22.
- The University of Chicago Medical Center (UCMC) enacts a universal-masking policy.
- Mayor Lori Lightfoot closes the lakefront to facilitate Chicagoans’ social distancing.
- University administrators announce that campus buildings will start to have restricted access regarding who may enter.
- UCMC taps perioperative nurses to cover staffing shortages due to COVID-19 on April 15.
- The University announces that the 533rd convocation will not be held on campus.
- Provost Ka Yee Lee announces that the University will not reduce tuition in response to remote learning after a month-long campaign by UChicago for Fair Tuition.
- The University announces it will begin resuming research activities.
- President Robert Zimmer announces the University will lose about $220 million due to the pandemic, not including losses in the medical division.